Enzymes+(3.8+and+7.6



- intro. to enzymes - how enzymes work animation... and another
 * 9/24/10**

Fun science fact that's not directly related to biology.

HW: //Tiger// book, pgs. 76, 77, 79

 * 9/27/10**


 * This protein stuff can be complex.**



Human Interactome


- I have recorded your completion of the online protein folding tutorial on PowerSchool - go over test and hand back

HW:

 * ===for reinforcement of protein concepts, go to The Science of Atoms and Molecules, select //Nucleic Acids and Proteins (v4)// and do section 4===
 * ===Tiger book, pg. 80, 82, 84===

- pH, temperature, concentration on enzyme activity - lab design component
 * 9/28/10**
 * critique and grade labs with rubrics
 * [[file:18 sample lab (no teacher comments).doc]][[file:18 sample lab 2.doc]][[file:9 sample lab (no teach. comments).doc]][[file:9 sample lab 2.doc]]
 * write up design for hair strength

HW:

 * ===quiz on proteins Thursday===
 * ===Tiger book, pg. 78 and 81 (graph analysis)===

- reassessment on //Elements, Carbs, Water, etc.// Thursday or Friday before or after school - review/ questions for Thursday's assessment
 * 9/29/10**
 * all protein A.S.
 * recognizing amino acid
 * condensation and hydrolysis reactions
 * enzymes: definition, factors affecting rate (pH, temperature, substrate concentration), recognize enzyme, substrate and enzyme/ substrate complex

- presenting data with graphs - discuss graphs for enzyme rate (exponential, decelerating, zero activity) - data presentation and graph format handout - write up design portion of hair strength labs in groups - peer assess with rubrics

HW: study for assessment
- assessment
 * 9/30/10**
 * all protein A.S.
 * recognizing amino acid
 * condensation and hydrolysis reactions
 * enzymes: definition, factors affecting rate (pH, temperature, substrate concentration)

HW:

 * ===DBQ on page 84 in //Tiger// book===
 * ===pg. 85-87 in //Tiger// book (induced fit, enzyme inhibition, metabolic pathways)===

- go over DBQ
 * 10/1/10**

1. OMP decarboxylase has the slowest uncatalyzed rate.
 * Data-based question: the effectiveness of enzymes, page 84**

2. OMP decarboxylase hs the highest catalyzed rate.

3. Ketosteroid isomerase 3.8 × 10^11, Nuclease 5.6 × 10^20, OMP decarboxylase 1.4 × 10^24

4. OMP decarboxylase is the most effective as it is the slowest reaction without a catalyst and the most rapid reaction with a catalyst.

5. Answer should refer to:
 * The substrate binds to the active site of the enzyme.
 * The binding leads to a conformational change in the enzyme that strains bonds within the substrate making it more reactive.
 * It makes collisions between substrates more effective in terms of promoting a reaction.

- activation energy animation - finish writing and peer editing hair strength lab design - discuss with class

HW; read graphing guidelines worksheets
- discuss enzyme inhibition (competitive and noncompetitive) - with examples (in period 8 only) - chains and cycles of enzyme catalyzed reactions w/ end product inhibition - graphing worksheets... bar graphs vs. frequency histograms (briefly in per. 2)
 * 10/4/10**

- inhibition examples (in period 2 only) - graphing worksheets... bar graphs vs. frequency histograms (briefly in per. 8) - hand back and go over //Proteins and Enzymes I// test - intro. to catalase lab
 * 10/5/10**

- catalase lab with Vernier oxygen sensors and pressure sensors
 * 10/6/10**

- Jmol catalase model - continue catalase lab
 * 10/7/10**

HW:

 * ===end of chapt. 7 questions (pg. 88), in //Tiger// book, due Tuesday===
 * ===test on enzymes Wednesday (10/13)===

- wrapped up catalase lab
 * 10/8/10**

- data processing of enzyme activity vs. substrate/ enzyme concentration - collect data points (each group give slope for each condition)
 * 10/11/10**

HW:

 * ===end of chapt. 7 questions (pg. 88), in //Tiger// book, due Tuesday (10/12)===
 * ===test on enzymes Wednesday (10/13)===

- discuss //Tiger// chapt. 7 review questions - review for protein/ enzyme test - reiterate the resources available for studying:
 * 10/12/10**
 * Raven and Johnson text (for enzymes, pg. 148-152 and 156)
 * Kimball's Biology Pages on enzymes
 * click4biology

**HW: study for test:**

 * ====**enzyme A.S. from this page**====
 * ====**Outline the role of condensation and hydrolysis in the relationships between monosaccharides,**====

**disaccharides and polysaccharides; between fatty acids, glycerol and triglycerides; and between amino** **acids and polypeptides.**

 * ====**Identify amino acids from diagrams showing their structure.**====
 * ====**Explain the four levels of protein structure, indicating the significance of each level.**====

- review for test
 * 10/13/10**

- test
 * 10/14/10**

We usually see maps associated strictly with geography. Here and here and here are very cool maps associated with science concepts. The site this came from (Edge.org) has lots of interesting stuff.
 * 10/19/10**

- group retake of test