9/24/10
- intro. to enzymes
- how enzymes work animation... and another

Fun science fact that's not directly related to biology.

HW: Tiger book, pgs. 76, 77, 79



9/27/10

This protein stuff can be complex.

ATPSynthase1.jpg
ATP synthase protein, showing complex tertiary and quaternary structure

Human Interactome


human_interactome
Human Interactome

- I have recorded your completion of the online protein folding tutorial on PowerSchool
- go over test and hand back

HW:


9/28/10
- pH, temperature, concentration on enzyme activity
- lab design component

HW:

  • quiz on proteins Thursday

  • Tiger book, pg. 78 and 81 (graph analysis)


9/29/10
- reassessment on Elements, Carbs, Water, etc. Thursday or Friday before or after school
- review/ questions for Thursday's assessment
  • all protein A.S.
  • recognizing amino acid
  • condensation and hydrolysis reactions
  • enzymes: definition, factors affecting rate (pH, temperature, substrate concentration), recognize enzyme, substrate and enzyme/ substrate complex

- presenting data with graphs
- discuss graphs for enzyme rate (exponential, decelerating, zero activity)
- data presentation and graph format handout
- write up design portion of hair strength labs in groups
- peer assess with rubrics

HW: study for assessment


9/30/10
- assessment
  • all protein A.S.
  • recognizing amino acid
  • condensation and hydrolysis reactions
  • enzymes: definition, factors affecting rate (pH, temperature, substrate concentration)

HW:

  • DBQ on page 84 in Tiger book

  • pg. 85-87 in Tiger book (induced fit, enzyme inhibition, metabolic pathways)



10/1/10
- go over DBQ

Data-based question: the effectiveness of enzymes, page 84
1. OMP decarboxylase has the slowest uncatalyzed rate.

2. OMP decarboxylase hs the highest catalyzed rate.

3. Ketosteroid isomerase 3.8 × 10^11, Nuclease 5.6 × 10^20, OMP decarboxylase 1.4 × 10^24

4. OMP decarboxylase is the most effective as it is the slowest reaction without a catalyst and the most
rapid reaction with a catalyst.

5. Answer should refer to:
  • The substrate binds to the active site of the enzyme.
  • The binding leads to a conformational change in the enzyme that strains bonds within the substrate making it more reactive.
  • It makes collisions between substrates more effective in terms of promoting a reaction.

- activation energy animation
- finish writing and peer editing hair strength lab design
- discuss with class

HW; read graphing guidelines worksheets


10/4/10
- discuss enzyme inhibition (competitive and noncompetitive)
- with examples (in period 8 only)
- chains and cycles of enzyme catalyzed reactions w/ end product inhibition
- graphing worksheets... bar graphs vs. frequency histograms (briefly in per. 2)

10/5/10
- inhibition examples (in period 2 only)
- graphing worksheets... bar graphs vs. frequency histograms (briefly in per. 8)
- hand back and go over Proteins and Enzymes I test
- intro. to catalase lab

10/6/10
- catalase lab with Vernier oxygen sensors and pressure sensors

10/7/10
- Jmol catalase model
- continue catalase lab

HW:

  • end of chapt. 7 questions (pg. 88), in Tiger book, due Tuesday

  • test on enzymes Wednesday (10/13)


10/8/10
- wrapped up catalase lab

10/11/10
- data processing of enzyme activity vs. substrate/ enzyme concentration
- collect data points (each group give slope for each condition)

HW:

  • end of chapt. 7 questions (pg. 88), in Tiger book, due Tuesday (10/12)

  • test on enzymes Wednesday (10/13)


10/12/10
- discuss Tiger chapt. 7 review questions
- review for protein/ enzyme test
- reiterate the resources available for studying:
  • Raven and Johnson text (for enzymes, pg. 148-152 and 156)
  • Kimball's Biology Pages on enzymes
  • click4biology

HW: study for test:

  • enzyme A.S. from this page

  • Outline the role of condensation and hydrolysis in the relationships between monosaccharides,

disaccharides and polysaccharides; between fatty acids, glycerol and triglycerides; and between amino acids and polypeptides.

  • Identify amino acids from diagrams showing their structure.

  • Explain the four levels of protein structure, indicating the significance of each level.


10/13/10
- review for test

10/14/10
- test

10/19/10
We usually see maps associated strictly with geography. Here and here and here are very cool maps associated with science concepts. The site this came from (Edge.org) has lots of interesting stuff.

- group retake of test